The causes of multiple sclerosis Use Prednisone

Multiple sclerosis - a neurological pathology characterized by progressive course with multiple lesions in the central nervous system and with fewer lesions in the peripheral nervous system. In neuroscience can find the terms "multiple sclerosis", "patchy sclerosis," "plaque sclerosis," "diffuse sclerosing encephalomyelitis", they are the symbol of the same disease buy prednisone online. Pathology flow wavelike character - chronic.

Previously, most of the people with MS living in countries far from the equator, at the present time a clear geographical distribution does not exist. In the past few decades it has been an increase of pathology in most regions of the globe, but still remains in the lead of countries with a temperate climate. There figures reach from 50 to 100 per 100 000 population.

Most suffer the woman, although about one-third of cases of multiple sclerosis accounted for the male population of the planet. Pathology manifests often at a young age, affecting active people from 20 to 45 years old - it's almost 60% of all cases. Most often, multiple sclerosis is diagnosed in people who are engaged in intellectual work.

In addition, scientists at a given time are revised age limits debut of the disease in the direction of their expansion. Thus, medical cases of MS are described in the age of two, as well as the age of 10-15 years. The number of patients in childhood varies on different data from 2 to 8% of the total number of cases. The group of risks is now composed of persons older than 50 years.

As a result of several factors, there is an increase transmittance blood-brain barrier (its main function - protecting the brain antigens from the damaging effects of their own immune system cells). As a result, in the brain receives a greater number of T lymphocytes and starts the process of inflammation. The result of such inflammation is the destruction of the myelin sheath of the nerve, as the immune system perceives myelin antigens as foreign. transmission of nerve impulses in the same volume becomes impossible and the person begins to suffer from the symptoms of the disease.

The causes of multiple sclerosis are multiple external and internal factors, so it is considered as a multifactorial pathology.

Particular attention is attracted by scientists following etiological factors:

Impact of viruses on the occurrence of the disease. This retroviruses, herpes viruses, measles and rubella virus, infectious mononucleosis, especially in combination with endogenous retroviruses. Adversely affects the transferred bacterial infections -. Streptococcal, staphylococcal, etc. However, the scientists came to the conclusion that there is no virus, which would directly lead to the development of the disease. However, they are triggering factors that support development and inducing inflammatory and autoimmune processes, thereby stimulating neurodegenerative changes.

Effect of chronic poisoning on the human body. Especially dangerous is the poisoning chemicals, organic solvents, metals, gasoline and so on. The negative factor is considered to be living in ecologically unfavorable area, especially in childhood.

Features of the diet. In this sense the danger are animal fats and proteins, and their excessive use under the age of 15 years. When a person suffers from obesity to 20 years of age, the risk of developing the disease had increased by 2 times. It is also shown that excessive consumption of salt causes abnormal activity of the immune system.

Genetic predisposition to develop the disease. This is particularly evident in the family history of multiple sclerosis. Risks of disease in blood relatives are from 3 to 10%.

Membership of the female sex, in all populations of patients prevail, it is women, however, the unfavorable course of the disease is typical for men.

Change of residence zone change affects the frequency of occurrence of the disease among migrated population.

There are cases of a sharp increase in the incidence in a limited area in a certain time period.

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